Can you inject mylan 345

In this case, people may continue to snort Valium and risk the effects of nasal problems, overdose, and dependence. Valium tablets are made with materials other than diazepam. These additional materials not only little effect, but can also cause further deterioration in the nasal cavity.

Snorting Valium, as well as other substances, can cause nasal problems such as inflammation of the nasal lining and damage to nasal membranes. Further exposure to harmful substances in the nose can also lead to infections in the lungs and other breathing problems.

Snorting Valium can cause permanent damage to nasal airways, which can have serious, long-term health consequences. The nose filters the air a person breathes, and damaging the nose can affect the air entering the lungs, which can cause infection and other problems. Snorting Valium can lead to overdose because the person is likely taking more than the recommended amount.

Crushing tablets and snorting them can result in consuming uncontrollable amounts of diazepam, which can be dangerous. When a person overdoses on Valium, they may fall into a deep sleep or coma, but still be able to breathe. Other symptoms of a Valium overdose include:. Any signs of an overdose should be treated as a medical emergency, and should be contacted immediately. Large amounts of diazepam can be dangerous and may cause serious consequences like brain damage and permanent disability.

As a benzodiazepine , Valium can be addictive. Snorting Valium, which is suggestive of abuse, can accelerate the process of developing addiction and dependence. Dependence occurs when a person requires Valium to avoid feeling sick. Because the brain and body have become used to having diazepam in the system, removing it causes the body to go through a period of adjustment that produces uncomfortable symptoms called withdrawal.

As a long-acting benzodiazepine, Valium withdrawal is likely to occur between days after last use. Symptoms can last as long as eight weeks and can be very uncomfortable, especially if the drug has been snorted or abused for longer than four months. Symptoms of Valium withdrawal may include:.

As a result, there may be difficulty in differentiating withdrawal symptoms from potential re-emergence or continuation of symptoms for which the benzodiazepine was being used. Tolerance to diazepam tablets may develop from continued therapy. Tolerance is a physiological state characterized by a reduced response to a drug after repeated administration i.

Tolerance to the therapeutic effect of diazepam tablets may develop; however, little tolerance develops to the amnestic reactions and other cognitive impairments caused by benzodiazepines. Overdose of benzodiazepines is usually manifested by central nervous system depression ranging from drowsiness to coma.

In mild cases, symptoms include drowsiness, confusion, and lethargy. In more serious cases, symptoms may include ataxia, diminished reflexes, hypotonia, hypotension, respiratory depression, coma rarely , and death very rarely.

Overdose of benzodiazepines in combination with other CNS depressants including alcohol may be fatal and should be closely monitored. Following overdose with oral benzodiazepines, general supportive measures should be employed including the monitoring of respiration, pulse, and blood pressure.

Vomiting should be induced within 1 hour if the patient is conscious. Gastric lavage should be undertaken with the airway protected if the patient is unconscious. Intravenous fluids should be administered. If there is no advantage in emptying the stomach, activated charcoal should be given to reduce absorption.

Special attention should be paid to respiratory and cardiac function in intensive care. General supportive measures should be employed, along with intravenous fluids, and an adequate airway maintained. Should hypotension develop, treatment may include intravenous fluid therapy, repositioning, judicious use of vasopressors appropriate to the clinical situation, if indicated, and other appropriate countermeasures.

Dialysis is of limited value. As with the management of intentional overdosage with any drug, it should be considered that multiple agents may have been ingested.

Flumazenil, a specific benzodiazepine-receptor antagonist, is indicated for the complete or partial reversal of the sedative effects of benzodiazepines and may be used in situations when an overdose with a benzodiazepine is known or suspected.

Prior to the administration of flumazenil, necessary measures should be instituted to secure airway, ventilation and intravenous access. Flumazenil is intended as an adjunct to, not as a substitute for, proper management of benzodiazepine overdose. Patients treated with flumazenil should be monitored for resedation, respiratory depression and other residual benzodiazepine effects for an appropriate period after treatment. The prescriber should be aware of a risk of seizure in association with flumazenil treatment, particularly in long-term benzodiazepine users and in cyclic antidepressant overdose.

Caution should be observed in the use of flumazenil in epileptic patients treated with benzodiazepines. Dosage should be individualized for maximum beneficial effect.

While the usual daily dosages given below will meet the needs of most patients, there will be some who may require higher doses. In such cases dosage should be increased cautiously to avoid adverse effects. Because of varied responses to CNS-acting drugs, initiate therapy with lowest dose and increase as required.

Not for use in pediatric patients under 6 months. To reduce the risk of withdrawal reactions, use a gradual taper to discontinue diazepam tablets or reduce the dosage. If a patient develops withdrawal reactions, consider pausing the taper or increasing the dosage to the previous tapered dosage level. The 2 mg tablets are white, round, scored tablets debossed with MYLAN over on one side and scored on the other side. They are available as follows:. The 5 mg tablets are orange, round, scored tablets debossed with MYLAN over on one side and scored on the other side.

The 10 mg tablets are green, round, scored tablets debossed with MYLAN over on one side and scored on the other side. Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.

What is the most important information I should know about diazepam tablets? Before you take diazepam tablets, tell your healthcare provider about all of your medical conditions, including if you:.

Tell your healthcare provider about all the medicines you take , including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking diazepam tablets with certain other medicines can cause side effects or affect how well diazepam tablets or the other medicines work. Do not start or stop other medicines without talking to your healthcare provider. How can I watch for early symptoms of suicidal thoughts and actions? Call your healthcare provider between visits as needed, especially if you are worried about symptoms.

Suicidal thoughts or actions can be caused by things other than medicines. If you have suicidal thoughts or actions, your healthcare provider may check for other causes.

These are not all the possible side effects of diazepam tablets. Call your doctor for medical advice about side effects. General information about the safe and effective use of diazepam tablets. Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use diazepam tablets for a condition for which they were not prescribed.

Do not give diazepam tablets to other people, even if they have the same symptoms that you have. They may harm them. You can ask your pharmacist or healthcare provider for information about diazepam tablets that is written for health professionals. Inactive ingredients: colloidal silicon dioxide, magnesium stearate, microcrystalline cellulose, pregelatinized starch corn and sodium lauryl sulfate.

Manufactured for: Mylan Pharmaceuticals Inc. Morgantown, WV U. Keep this and all medication out of the reach of children. DailyMed will deliver notification of updates and additions to Drug Label information currently shown on this site through its RSS feed. DailyMed will deliver this notification to your desktop, Web browser, or e-mail depending on the RSS Reader you select to use. Due to inconsistencies between the drug labels on DailyMed and the pill images provided by RxImage , we no longer display the RxImage pill images associated with drug labels.

We anticipate reposting the images once we are able identify and filter out images that do not match the information provided in the drug labels. Drug Label Info. NDC National Drug Code - Each drug product is assigned this unique number which can be found on the drug's outer packaging.

Drug Label Information Updated March 1, If you are a consumer or patient please visit this version. Reserve concomitant prescribing of these drugs in patients for whom alternative treatment options are inadequate.

Limit dosages and durations to the minimum required. The risks of dependence and withdrawal increase with longer treatment duration and higher daily dose. Abrupt discontinuation or rapid dosage reduction of diazepam tablets after continued use may precipitate acute withdrawal reactions, which can be life-threatening.

Elimination The initial distribution phase is followed by a prolonged terminal elimination phase half-life up to 48 hours. Pharmacokinetics in Special Populations Children In children years old the mean half-life of diazepam has been reported to be 18 hours. Newborns In full term infants, elimination half-lives around 30 hours have been reported, with a longer average half-life of 54 hours reported in premature infants of weeks gestational age and days post-partum.

Geriatric Elimination half-life increases by approximately 1 hour for each year of age beginning with a half-life of 20 hours at 20 years of age. Hepatic Insufficiency In mild and moderate cirrhosis, average half-life is increased. Risks from Concomitant Use with Opioids Concomitant use of benzodiazepiones, including diazepam tablets, and opioids may result in profound sedation, respiratory depression, coma, and death.

Abuse, Misuse, and Addiction The use of benzodiazepines, including diazepam tablets, exposes users to the risks of abuse, misuse, and addiction, which can lead to overdose or death. Acute Withdrawal Reactions The continued use of benzodiazepines, including diazepam tablets, may lead to clinically significant physical dependence. Pregnancy An increased risk of congenital malformations and other developmental abnormalities associated with the use of benzodiazepine drugs during pregnancy has been suggested.

Labor and Delivery Special care must be taken when diazepam tablets are used during labor and delivery, as high single doses may produce irregularities in the fetal heart rate and hypotonia, poor sucking, hypothermia, and moderate respiratory depression in the neonates. Nursing Mothers Diazepam passes into breast milk. General If diazepam tablets are to be combined with other psychotropic agents or anticonvulsant drugs, careful consideration should be given to the pharmacology of the agents to be employed - particularly with known compounds that may potentiate the action of diazepam, such as phenothiazines, narcotics, barbiturates, MAO inhibitors and other antidepressants see Drug Interactions.

Risks from Concomitant Use with Opioids Advise both patients and caregivers about the risks of potentially fatal respiratory depression and sedation when diazepam tablets are used with opioids and not to use such drugs concomitantly unless supervised by a health care provider.

Abuse, Misuse, and Addiction Inform patients that the use of diazepam tablets, even at recommended dosages, exposes users to risks of abuse, misuse, and addiction, which can lead to overdose and death, especially when used in combination with other medications e. Withdrawal Reactions Inform patients that the continued use of diazepam tablets may lead to clinically significant physical dependence and that abrupt discontinuation or rapid dosage reduction of diazepam tablets may precipitate acute withdrawal reactions, which can be life-threatening.

Drug Interactions Opioids The concomitant use of benzodiazepines and opioids increases the risk of respiratory depression because of actions at different receptor sites in the CNS that control respiration.

Alcohol Concomitant use with alcohol is not recommended due to enhancement of the sedative effect. Compounds Which Inhibit Certain Hepatic Enzymes There is a potentially relevant interaction between diazepam and compounds which inhibit certain hepatic enzymes particularly cytochrome P 3A and 2C Phenytoin There have also been reports that the metabolic elimination of phenytoin is decreased by diazepam. Pediatric Use Safety and effectiveness in pediatric patients below the age of 6 months have not been established.

Geriatric Use In elderly patients, it is recommended that the dosage be limited to the smallest effective amount to preclude the development of ataxia or oversedation 2 mg to 2. Hepatic Insufficiency Decreases in clearance and protein binding, and increases in volume of distribution and half-life have been reported in patients with cirrhosis.

The following have also been reported: Central Nervous System: confusion, depression, dysarthria, headache, slurred speech, tremor, vertigo Gastrointestinal System: constipation, nausea, gastrointestinal disturbances Special Senses: blurred vision, diplopia, dizziness Cardiovascular System: hypotension Psychiatric and Paradoxical Reactions: stimulation, restlessness, acute hyperexcited states, anxiety, agitation, aggressiveness, irritability, rage, hallucinations, psychoses, delusions, increased muscle spasticity, insomnia, sleep disturbances, and nightmares.

Urogenital System: incontinence, changes in libido, urinary retention Skin and Appendages: skin reactions Laboratories: elevated transaminases and alkaline phosphatase Other: changes in salivation, including dry mouth, hypersalivation Antegrade amnesia may occur using therapeutic dosages, the risk increasing at higher dosages. Postmarketing Experience Injury, Poisoning and Procedural Complications There have been reports of falls and fractures in benzodiazepine users.

Abuse Diazepam tablets are a benzodiazepine and a CNS depressant with a potential for abuse and addiction. Dependence Physical Dependence Diazepam tablets may produce physical dependence from continued therapy. Acute Withdrawal Signs and Symptoms Acute withdrawal signs and symptoms associated with benzodiazepines have included abnormal involuntary movements, anxiety, blurred vision, depersonalization, depression, derealization, dizziness, fatigue, gastrointestinal adverse reactions e.

Use all seizure medications as directed and read all medication guides you receive. Do not change your dose or stop using a medicine without your doctor's advice. Do not use diazepam rectal for long-term daily use to prevent seizures or your seizures could get worse or happen more often. You should not use this medicine more than 5 times in 1 month, or to treat more than 1 episode every 5 days.

Store at room temperature away from moisture, heat, and light. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription. After giving a dose of diazepam rectal, empty the syringe into a toilet and flush, or into a sink and rinse down the drain.

Do not reuse the syringe. Throw it away where children and pets cannot get to it. Overdose symptoms may include extreme drowsiness, loss of balance or coordination, limp or weak muscles, slow breathing, or fainting. Grapefruit may interact with diazepam and lead to unwanted side effects. Avoid the use of grapefruit products. Avoid driving or hazardous activity until you know how this medicine will affect you.

Dizziness or drowsiness can cause falls, accidents, or severe injuries. Get emergency medical help if you have signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat. A person caring for you should seek emergency medical attention if you have weak or shallow breathing, if you are hard to wake up, or if you stop breathing. The sedative effects of diazepam rectal may last longer in older adults.

Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are using diazepam rectal. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Using diazepam with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death.

Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, prescription cough medicine, or medicine for depression or seizures. Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Other drugs may affect diazepam, including prescription and over-the-counter medicines, vitamins, and herbal products.

Tell your doctor about all your current medicines and any medicine you start or stop using. Learn More About Us. DiazePAM Diazepam.